The MP4601 is an integrated white LED driver. It can be applied with MPS patent pending technology to drive up to 60 inch or larger size LCD TV backlighting, in which the LED string voltage can be up to 350V. The novel technology can leverage the LED drive power by regulating only small portion of the LED drive voltage. As a result, working together with a fixed high voltage source, a low voltage LED driver can be used to drive the high voltage LED strings with super high power density, high efficiency and low cost due to the low voltage stress, high switching frequency, and smaller size of passive components. MP4601 is a current mode controlled buck-boost regulator. With a 12V input VINL and a high voltage source VINH, it can deliver a regulated voltage (VINH to VINH+63V) to drive a LED string with up to 100 LEDs. It can drive an external switch, which is in series with the LED string, to achieve over 1:1000 dimming ratio. Analog dimming can be applied in the same time to further improve the dimming ratio. Fault protection includes LED open strings protection, output short circuit protection, cycle?y?ycle peak current limiting, and thermal shutdown. MP4601 is available in TSSOP16-EP and SOIC16 packages.